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9 Rare Side Effects That No One Will Ever Tell You About the Comirnaty Vaccine


The Comirnaty COVID-19 vaccine 💉, developed by Pfizer-BioNTech, has proven to be an effective tool in combating the COVID-19 pandemic. Like all vaccines, it can cause side effects in some people.

6 Common Side Effects of the Comirnaty Vaccine

Common Side Effects of the Comirnaty Vaccine

A messenger RNA (mRNA) vaccine called Comirnaty was created by Pfizer-BioNTech and is approved for use against COVID-19. It has successfully prevented COVID-19 after undergoing extensive testing that showed both safety and effectiveness. The Comirnaty vaccination can have certain adverse effects, however the majority of them are minor and transient. Following vaccination with the Comirnaty vaccine, common adverse effects include:

1.Injection site reactions

Pain, redness, or swelling at the injection site are common side effects that usually resolve within a few days.


Feeling tired or exhausted is a commonly reported side effect. It typically lasts for a few days.


Some individuals may experience mild to moderate headaches after vaccination. These headaches usually go away on their own.

4.Muscle pain and joint pain

Muscle aches and joint pain can occur as a result of the immune response triggered by the vaccine. These symptoms are usually temporary.

5.Chills or fever

Some people may experience a low-grade fever or chills after receiving the vaccine. These symptoms are generally mild and resolve within a day or two.


Feeling nauseous or having an upset stomach is a reported side effect, but it is usually temporary.

Rare side effects that no one will tell you

While rare, some individuals may experience more serious side effects. These include:

  • Severe allergic reactions (anaphylaxis): This is extremely rare and usually occurs within a few minutes to an hour after vaccination. Vaccine providers are equipped with medications to manage this immediate reaction.
  • Myocarditis and pericarditis: These are inflammations of the heart or the lining around the heart, respectively. They are rare, especially when compared to the risk of heart complications from COVID-19 itself.

What to avoid after the Comirnaty vaccine

What to avoid after the Comirnaty vaccine

Here are some examples of activities that may cause side effects or should be avoided after receiving the Comirnaty COVID-19 vaccine:

  1. Strenuous exercise: Avoid overexertion and resume exercise routines gradually. This is to avoid putting excessive stress on the immune system.
  2. Massages: Avoid massages around the injection site arm for 2-3 days. Massage pressure could exacerbate pain and swelling.
  3. Hot tubs or saunas: Avoid for a couple days after vaccination as the hot temperatures may worsen immune response.
  4. Cosmetic fillers: It’s recommended to schedule these a few weeks before or after vaccination as rare swelling at the filler site has been reported.
  5. Dental procedures: Routine procedures should be postponed until a few days after getting the vaccine to avoid confusing vaccine side effects with dental work impacts.
  6. Alcohol use: Avoid excessive alcohol intake which may impair immune response.
  7. Smoking tobacco: Refrain from smoking for a few days after the vaccine to support healthy immune function.

Air travel: Wait at least 3 days after each vaccine dose before air travel if possible to monitor for any adverse effects.

Drugs that cause side effects with the COVID-19 vaccine (Comirnaty)

Here are some examples of medicines that may potentially interact with or cause side effects when taken after receiving the Comirnaty COVID-19 vaccine:
  • Anti-inflammatory medicines like ibuprofen (Advil, Motrin) or naproxen (Aleve). These may temporarily reduce the immune response to the vaccine. It’s recommended to avoid taking these types of medicines for a couple days before and after getting vaccinated.
  • Blood thinners like warfarin (Coumadin). The vaccine may increase the blood-thinning effects. Your doctor may recommend additional monitoring of your blood work.
  • Immunosuppressants like steroids or medications for rheumatoid arthritis, psoriasis, or Crohn’s disease. These could reduce the effectiveness of the vaccine. Timing of taking these medicines around vaccination may need to be adjusted.
  • Medications that interact with polyethylene glycol (PEG), which is an ingredient in the mRNA vaccines. An example is methotrexate for autoimmune conditions. Allergies to PEG could increase risk of immediate allergic reactions.
  • Any medications causing drowsiness or impairing your immune system response. Ideal to avoid starting these medicines for a few days before or after vaccination if possible.
Your doctor should check the Comirnaty vaccine’s component list and your medical history to determine any potential drug interactions and dosage timing. Talk to your provider if you have any worries regarding side effects.

6 ways to Reduce the side effects of the Comirnaty Vaccine (Guide)

What to dp after the Comirnaty vaccine

To reduce the side effects of the Comirnaty vaccine, you can follow these steps:

  1. Stay hydrated: Drink plenty of water before and after receiving the vaccine. Staying hydrated can help alleviate some common side effects.
  2. Apply a cold compress: If you experience pain, swelling, or redness at the injection site, applying a cold compress can help reduce inflammation and provide relief.
  3. Take over-the-counter pain relievers: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or acetaminophen can help alleviate pain, headache, or fever that may occur after vaccination. However, it’s always best to consult with your healthcare provider or follow the instructions provided with the vaccine for specific recommendations.
  4. Rest and take it easy: Your body may need time to recover after vaccination. Make sure to get enough rest and avoid strenuous activities for a day or two, if possible.
  5. Monitor your symptoms: Keep track of any side effects you experience and their severity. If you notice any unusual or severe symptoms, contact your healthcare provider for further guidance.
  6. Follow post-vaccination guidelines: The vaccine’s manufacturer or healthcare provider may provide specific guidelines for managing side effects. It’s important to follow these instructions for the best possible outcome.

Mild adverse reactions show that the vaccine has stimulated the immune system. If you have any worries or enquiries, speak with your healthcare professional who can offer you specific guidance.

Your Comments and Suggestions?

In the comments section of this page, you can let us know if there was anything we missed or if you have any further knowledge on the comirnaty vaccine.

Daniel Anderson
Daniel Anderson is a distinguished name in the field of medical and healthcare expertise, recognized for his profound contributions to the industry. With an unwavering commitment to improving healthcare systems and patient outcomes, Daniel has established himself as a prominent figure in the medical community.

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